Cryo-electron microscopy reveals ribosome ‘threading’ a protein into its membrane…

A combination of fuzzy images from Cyro EM and molecular modelling of MANY (2.7 million) atoms reveals how ribosome inserts a protein into its membrane:

http://esciencenews.com/articles/2011/04/17/researchers.get.a.first.look.mechanics.membrane.proteins

Prof. Klaus Schulten leads this project. The software involved Molecular Dynamics Flexible Fitting (MDFF) is freely available.

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